LipidDB ID

LipidDB-10090-00033

Entry Name

UniProt Accession

O70480; Q9D095;

Theoretical PI

6.75

Molecular Weight

16352.76

Genbank Protein ID

AAC15776.1; BAB27774.1; BAB31171.1;

Genbank Nucleotide ID

AF061516; AK011678; AK018344;

Protein Name

Vesicle-associated membrane protein 4

Protein Synonyms/Alias

VAMP-4;

Gene Name

Vamp4

Gene Synonyms/Alias

Created Date

21-FEB-2001

Organism

Mus musculus (Mouse)

NCBI Taxa ID

10090

Reference

[1] Predicted from GPS-Lipid

Functional Description

Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule (By similarity).

Sequence Annotation

Topological domain: 1 118 Cytoplasmic.
Transmembrane: 119 139 Helical; Anchor for type IV membraneprotein.
Topological domain: 140 141 Vesicular.
Domain: 52 112 v-SNARE coiled-coil homology.
Modified residue: 17 17 Phosphoserine.
Modified residue: 30 30 Phosphoserine.

Protein Length

141 AA.

Protein Sequence
(Canonical)

FASTA
(Canonical)

Gene Ontology

GO:0005794; C:Golgi apparatus; IDA:MGI
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW
GO:0031201; C:SNARE complex; IDA:MGI
GO:0005802; C:trans-Golgi network; IDA:MGI
GO:0043001; P:Golgi to plasma membrane protein transport; IMP:MGI
GO:0042996; P:regulation of Golgi to plasma membrane protein transport; IMP:MGI

Interpro

InterPro; IPR001388; Synaptobrevin
InterPro; IPR016444; Synaptobrevin/VAMP_met/fun

Pfam

Pfam; PF00957; Synaptobrevin;

SMART

PROSITE

PROSITE; PS00417; SYNAPTOBREVIN;
PROSITE; PS50892; V_SNARE;

PRINTS

PRINTS; PR00219; SYNAPTOBREVN;